Control of the thyroid by iodine. Iodide is known to control thyroid function. Its main effects are to decrease the response of the thyroid to thyrotropin (TSH); to acutely inhibit its own oxidation; to reduce its trapping after a delay; and, at high concentrations, to inhibit thyroid hormone secretion12).Small changes in iodine intake are sufficient to reset …Web
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With a high iodine concentration (100 μM), the MAPK1 signaling pathway was activated significantly in thyroid follicular epithelial cells, which means that in normal thyroid cells, high iodine may lead to the imbalance of the miR-422a/MAPK1 pathway. Considering that they only conducted functional experiments in two iodine …Web
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Iodine concentrations ranged from < 0.002 to 1.22 mg/L, with a mean of 0.19 mg/L; 42% of the samples had high iodine concentrations. The levels were higher in the east than in the west, and most of the samples with high iodine concentrations were obtained from sites east of the boundary between the Cangxian uplift and the Huanghua …Web
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2. Sources of Dietary Iodine. Iodine content in food is highly variable, and is low in the majority of food and beverages. In drinking water, the iodine quantity is affected by a number of factors, including the iodine abundance in the soil, vicinity to seawater, and agricultural runoff [].In China, for example, the iodine concentration in water may be …Web
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Exposure to high concentrations of iodine might also decrease the release of thyroid hormone, as reported in several small studies that show mild decreases in serum levels of thyroid hormone and increases in the serum level of TSH to the upper limit of the normal range. 10–12 Administration of iodine to patients with severe hyperthyroidism or ...Web
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1. Introduction. Iodine is an essential trace micronutrient in human health used in the biosynthesis of thyroid hormones, which regulate cellular metabolism, growth, and development throughout the lifespan [1,2].Iodine deficiency remains a global public health concern since it increases neonatal mortality and is a preventable cause of …Web
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Aims. To compare the staining properties of the I 2 species with other topical iodine disinfectants; to evaluate if the concentrations of I 2 in diluted PVP-I used to reduce severe acute respiratory syndrome coronavirus-2 in the nasal cavity are potentially cytotoxic; and to determine if high concentrations of I 2 can be delivered beyond the stratum …Web
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The recommended intake of iodine by the World Health Organization is 150 mcg per day for adults over 12 years of age and 250 mcg per day for pregnant and lactating women; the median urinary iodine concentration (UIC) should be controlled at 100-200 mcg per day to ensure that the population has an appropriate iodine nutritional status …Web
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A high-iodine groundwater probability prediction map covering all of China was produced based on the ANN model. The high-risk areas (defined here as having a high-iodine probability exceeding 0.5) covered about 19.8% of the country and were mainly concentrated in the central provinces of Henan, Shaanxi, and Shanxi, the eastern …Web
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However, several studies report that iodine supplements at moderately high concentration are well tolerated in euthyroid subjects and that only high doses (>30 mg/day), mainly as I −, generate hypothyroidism and goiter, which rapidly revert to normal when these individuals stop taking iodine at high concentrations, see Table 2 [15,18].Web
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There are 30 million people living in the high iodine water areas distributed in 734 towns in China . One of the effective measures to prevent excess iodine intake is to sell non-iodized salt in the market in high iodine water areas; the water authorities seldom pay attention to the iodine concentration in the water improvement program.Web
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The sources and primary mechanisms of high iodine concentration in deep groundwater are rarely reported, thereby restricting the development and utilization of the related groundwater resources. To address these issues, 194 deep groundwater samples were collected from the Zhangwei watershed in the North China Plain, China, to analyze …Web
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A case-control study among adolescents aged 8 to 16 found that high urinary iodine concentration strongly correlated to decreased risk of depression . In contrast, a follow-up study of healthy pregnant women reported that pregnant women who took additional iodine-containing vitamin supplementation had higher depression test scores …Web
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Drinking water typically has an iodine content of approximately 1−10 μg/L. 53 Groundwater high in iodine is increasingly reported in the literature, including in Algeria, 40, 41 Argentina, 54 China, …Web
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The iodine-replete healthy adult has about 15–20 mg of iodine, 70%–80% of which is contained in the thyroid [ 6 ]. Median urinary iodine concentrations of 100–199 mcg/L in …Web
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However, iodine is present in concentrations up to several thousand-fold higher than these amounts in medications, supplements and in the iodinated contrast agents used for radiologic studies . In some susceptible individuals, the use of these iodine-containing …Web
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The mean urinary iodine concentration was 124 µg/L, indicating the achievement of an adequate iodine intake without any differences between rural and urban areas. ... Despite some concerns related to high iodine exposure risks (hyperthyroidism, thyroid autoimmunity, and a relative increase in the risk of papillary thyroid cancer), the …Web
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cases, radioactive iodine uptake may be high even in the presence of euthyroid- ism; furthermore, the B.M.R. may be elevated because of the presence of other diseases that …Web
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Iodine is a crucial trace element for the human body and the basic raw material for the synthesis of thyroid hormones. Oral inorganic iodine includes dietary iodine and therapeutic iodine, both of which are closely associated with thyroid immunity and metabolism. Graves' disease (GD), also known as diffuse toxic goiter, is characterized by …Web
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High iodine intakes can also cause thyroid gland inflammation and thyroid cancer. Getting a very large dose of iodine (several grams, for example) can cause burning of the mouth, …Web
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Since urinary iodine concentration (UIC) is the recommended method to assess iodine status in populations, only studies that clearly reported both Tg and UIC were included. For the purpose of this review, a median Tg <13 μg/L and a median UIC ≥100 μg/L (UIC ≥150 μg/L for pregnant women) were used to indicate adequate iodine status.Web
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iodine value, in analytical chemistry, measure of the degree of unsaturation of an oil, fat, or wax; the amount of iodine, in grams, that is taken up by 100 grams of the oil, fat, or wax. …Web
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Median urinary iodine concentrations of 100–199 mcg/L in children and adults, ... Breast tissue has a high concentration of iodine, especially during pregnancy and lactation [4,75]. Some research suggests that iodine supplementation might …Web
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Taking 100 μg/L ≤ UIC < 300 μg/L (UIC = urinary iodine concentration) as the reference group, the odds ratio (OR) regarding high iodine levels and goiter …Web
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The median urinary iodine concentration (UIC) of a population reflects the total iodine intake from all sources and can accurately identify populations with excessive iodine intakes. Our review …Web
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Thus, high urinary iodine concentration does not reflect a disease state yet, but if persists on repeated urine sample, further blood tests is recommended. Urinary iodine reflects the food consumption taken overnight, and it is just an immediate biomarker (short-term reflection) for iodine intake. Thus, the long-term reflection of iodine intake ...Web
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High iodine concentrations were also obtained for different kinds of whey protein isolates and concentrates, with an average iodine concentration of 4,348 µg/kg (da Silva et al., 2016). Such results suggest that iodine is likely embedded in whey proteins, but specific and dedicated studies are recommended to confirm this empirical speculation ...Web
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A national survey in 1995, when salt iodine was 16.2 mg/kg, showed that iodine status was adequate with a median urinary iodine concentration (UIC) of 164.8 µg/L, yet goiter prevalence was high, at 20.4% .Web
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Request PDF | On Apr 5, 2022, Zhiyuan Zhang and others published Chemically Stable Guanidinium Covalent Organic Framework for the Efficient Capture of Low-Concentration Iodine at High Temperatures ...Web
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The sole ionic dimer is ioxaglate, which has an iodine concentration of 320 mg/mL and an osmolality of 600 mOsm/kg H 2 O. Non‐ionic dimer iodixanol has an iodine concentration at 320 mg/mL and the same osmolality as plasma, but its high viscosity (26 cPs at 37°C) limits its clinical application. The osmolality of ionic monomers is about ...Web
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As there are also some countries that have high concentrations of iodine in water, such as Djibouti and Qatar, this suggestion might be applicable. Second, from the 2020 China National Iodine Deficiency Disorders Surveillance results, at provincial level, the iodine nutrition levels of children in all provinces in China were at a sufficient ...Web
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The highest concentration of iodine in the human body is found in the thyroid, which contains 70–80% of the total iodine content (15–20 mg). Muscle and eyes also contain high iodide concentrations (6,8). Iodine is an essential element in the synthesis of the thyroid hormones thyroxine (T4) andWeb
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Seaweed-Derived Iodine Intake. Although the concentration of iodine in seawater is relatively low (approx. 58 µg/L), its massive abundance makes it the major source of iodine on the planet. Iodine in sea water is mainly present as I − and IO 3, with I − predominating in surface waters while IO 3 forms the greatest proportion in deep water .Web
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Breast tissue has a high concentration of iodine, especially during pregnancy and lactation [4,75]. Some research suggests that iodine supplementation might be helpful for fibrocystic breast disease, although a specific mechanism of action has not been established and data are limited.Web
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Such variations was discovered on GNRs under the high concentration of iodide. Whether this phenomenon can take place on other gold nanomaterials at a low iodide level remains unknown. In the present study, a novel and simple iodide colorimetric assay was proposed based on inducing the morphological transition of GNSs. This …Web
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Pure iodine is a bluish-black and lustrous solid. The iodine element ranks the 60th in terms of abundance (0.46 ppm in Earth's crustal rocks), and its concentration is about 50–60 μg L −1 in ocean water [15]. Marine organisms, especially brown algae or seaweeds can accumulate high iodine concentrations.Web
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The immediate indicator of iodine intake is the concentration of iodine in urine, but the indicator of iodine intake in the longer term of several months is thyroglobulin (Tg). ... Adults living in iodine-deficient regions carry a high risk of goiter, thyroid nodules and hyperthyroidism. Subclinical hyperthyroidism, as a common and frequently ...Web
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A high concentration of radioactive iodine destroys the tissues of the thyroid gland and reduces the production of hormones. Iodine is also found in drugs, including class III anti-arrhythmic Amiodarone (75 mg of iodine in one 200 mg tablet), the use of which may cause both hypo and hyperthyroidism . Oral and intravenous (i.v.) …Web
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