Effect of thallium (Tl +) on horizontal, vertical and ambulatory activities. Rats received either water as vehicle (controls) or a single administration of thallium acetate (8 or 16 mg/kg, i.p.). Seven days later, animals from all groups were challenged during 60 …Web
ادامه مطلب
DOI: 10.1016/0041-008X(81)90019-3 Corpus ID: 23244052; Effects of thallium, nickel, and cobalt administration of the lipid peroxidation in different regions of the rat brain.Web
ادامه مطلب
Tl + (30 mg/kg; 4 h) administered to rats produced toxic effects and altered the morphology and function of kidney. The magnitude of distribution and damage was followed by the ileum, stomach, and liver …Web
ادامه مطلب
Occupational exposure to thallium (Tl+) is known to be responsible for severe neurological manifestations in humans, including ataxia and paralysis; however, little is known yet about the precise mechanism of toxicity elicited by this heavy metal at sublethal doses and its brain distribution after chronic or subchronic exposures resulting from …Web
ادامه مطلب
The following study investigated the ability of exogenous MT to protect against oxidative damage induced by thallium (TI) in rat liver. Male Wistar rats were divided into four groups; a control and three experimental groups. ... Delayed effects of thallium in the rat brain: regional changes in lipid peroxidation and behavioral markers but ...Web
ادامه مطلب
Semantic Scholar extracted view of "Delayed effects of thallium in the rat brain: regional changes in lipid peroxidation and behavioral markers, but moderate alterations in antioxidants, after a single administration." by S. Galván‐Arzate et al.Web
ادامه مطلب
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy.Web
ادامه مطلب
Thallium (TI) is one of the most toxic heavy metals. Human exposure to Tl occurs through contaminated drinking water and from there to food, a threat to health. Recently, environmental contamination by Tl has been reported in several countries, urging the need for studies to determine the impact of endogenous and exogenous mechanisms …Web
ادامه مطلب
Thallium (Tl) is released into the environment, where is present at very low levels, from both natural and anthropogenic sources. Tl is considered as one of the most toxic heavy metals; it is a non-essential metal, present in low concentrations in humans. Tl toxicity causes dermatological and gastrointestinal diseases and disorders of the nervous …Web
ادامه مطلب
The clinical presentation of thallium toxicity can vary depending on the type, severity, and timeframe of the exposure. Acute thallium poisoning is primarily characterized by gastrointestinal, neurological, and dermatological symptoms, while neurologic findings predominate with chronic exposure and tend to progress, even …Web
ادامه مطلب
TOXICOLOGY AND APPLIED PHARMACOLOGY 57, 8- 13 (1981) Effects of Thallium, Nickel, and Cobalt Administration on the Lipid Peroxidation in Different Regions of the Rat Brain MAHDI HASAN AND S. FATEHYAB ALI Brain Research Center, Jawaharlal Nehru Medical College, Aligarh Muslim University, ALIGARH-202001, India Received …Web
ادامه مطلب
Thallium (Tl) is a trace metal enriched in wastewaters associated with mining and smelting of base metals. The toxicity of Tl to aquatic biota is poorly understood, particularly with respect to its sublethal effects. In this study, phototactic behavioural responses of naïve (i.e. no previous exposure to Tl) Daphnia magna, a key regulatory …Web
ادامه مطلب
The long‐term prognosis of thallium poisoning depends on the total dose ingested, the timing of treatment, and the individual susceptibility of each patient (Huang et al., 2014). Most of the symptoms of thallium poisoning can be completely reversed, but mild or moderate neurologic sequelae may last for a long time.Web
ادامه مطلب
Delayed effects of thallium in the rat brain: regional changes in lipid peroxidation and behavioral markers, but moderate alterations in antioxidants, after a single administration. Sign in | Create an account. https://orcid. Europe PMC ...Web
ادامه مطلب
About the neurotoxicity of thallium is related to its preferential effects in some brain regions [39], being the differential accumulation of thallium in brain topography a possible explanation ...Web
ادامه مطلب
Thallium acetate reduced survival, delayed development, caused behavioral changes, induced responses inherent to oxidative stress, and serious damage to …Web
ادامه مطلب
Based on the data implicating GTN and NO in migraine and inflammation, we investigated the delayed effects of GTN infusion on gene expression and inflammatory markers in rodent dura mater. The dura mater and particularly its attendant large blood vessels are implicated in migraine pain and are among the few intracranial tissues that …Web
ادامه مطلب
Galván-Arzate S, Pedraza-Chaverrí J, Medina-Campos ON, Maldonado PD, Vázquez-Román B, Ríos C, Santamaría A (2005) Delayed effects of thallium in the rat brain: regional changes in lipid peroxidation and behavioral markers, but moderate alterations in antioxidants, after a single administration. Food Chem Toxicol …Web
ادامه مطلب
Delayed effects of thallium in the rat brain: regional changes in lipid peroxidation and behavioral markers, but moderate alterations in antioxidants, after a single administration Author(s) Galván-Arzate, S; Pedraza-Chaverrí, J; Medina-Campos, ON; Maldonado, PD; Vázquez-Román, B; Ríos, C; Santamaría, AWeb
ادامه مطلب
Time course ofThallium accumulation in brain was found to be considerably more rapid in the hypothalamus than in other regions, particularly the cortex, suggesting differences in thallium entry into brain parenchyma. The content of thallium in seven body organs and eight brain regions of rats acutely exposed to Tl2SO4 was compared. Rats received a …Web
ادامه مطلب
Delayed effects of neonatal hippocampal damage on haloperidol-induced catalepsy and apomorphine-induced stereotypic behaviors in the rat ... (l.0 mg/kg i.p.) at 12.00 h. Starting 45 min later, the rat front paws were placed on a horizontal wooden bar (1.25 cm in diameter) suspended either 9.5 cm for PD35 rats or I I ~ 5.20 i -4,52 I Fig. 1 ...Web
ادامه مطلب
Semantic Scholar extracted view of "Thallium distribution in organs and brain regions of developing rats." by S. Galván‐Arzate et al.Web
ادامه مطلب
Animals of various ages were injected with thallium and regional brain content in cortex, hypothalamus and cerebellum was analyzed 1 day later (Fig. 4). Animals did not show differences in the thallium contents in brain regions until 5 days after birth, when cortical concentration was less than that of the newborn.Web
ادامه مطلب
Thallium (Tl) is a toxic heavy metal responsible for noxious effects in living organisms. As a pollutant, Tl can be found in the environment at high concentrations, especially in industrial areas. Systemic toxicity induced by this toxic metal can affect cell metabolism, including redox alterations, mitochondrial dysfunction, and activation of ...Web
ادامه مطلب
Thallium is a heavy metal that is known to induce a broad spectrum of adverse health effects in humans including alopecia, neurotoxicity, and mortality following high dose acute poisoning events. Widespread human exposure to thallium may occur via consumption of contaminated drinking water; limited toxicity data are available to …Web
ادامه مطلب
Semantic Scholar extracted view of "Delayed effects of thallium in the rat brain: regional changes in lipid peroxidation and behavioral markers, but moderate alterations in …Web
ادامه مطلب
Abstract. Thallium was once commonly used as a rodent or ant killer, but many countries have banned such use due to unintentional or criminal poisonings of humans. A common initial clinical manifestation of thallium poisoning is gastrointestinal symptoms followed by delayed onset of neurological symptoms and alopecia.Web
ادامه مطلب
Introduction Thallium (Tl +) toxicity remains as a serious health issue worldwide. The persistent use of this metal for several industrial purposes contributes to …Web
ادامه مطلب
Galván-Arzate S, Pedraza-Chaverrí J, Medina-Campos ON, Maldonado PD, Vázquez-Román B, Ríos C, Santamaria A (2005) Delayed effects of thallium in the rat brain: regional changes in lipid peroxidation and behavioral markers, but moderate alterations in antioxidants, after a single administration. Food Chem Toxicol 43:1037–1045Web
ادامه مطلب
At these dose levels, thallium also selectively altered the patterns of behavior. The study suggests that the target regions of thallium in the brain include the cortex, the cerebellum and the brainstem. The dose-response relationships, found for certain pairs of behavioral acts, were correlated with biochemical changes in one or more brain ...Web
ادامه مطلب
The Timm-Nissl atlas is based on a historical collection of rat brain sections stained with Haug's version 43 of Timm's method 40, in the following referred to as Timm-Haug73, developed for bulk-staining of serial sections, and used to comprehensively map the Timm-staining pattern in the rat brain 43 and specifically the hippocampal ...Web
ادامه مطلب
Symptoms of thallium toxicity are diverse in both humans and animals. The nervous system as a target organ of thallium is supported by observations from human case reports and animal studies. Relatively high doses of thallium caused neurological symptoms in humans (e.g., paresthesia of the hands and feet, weakness, tremors, coma, and convulsions).Web
ادامه مطلب
Delayed effects of thallium in the rat brain: regional changes in lipid peroxidation and behavioral markers, but moderate alterations in antioxidants, after a single administration …Web
ادامه مطلب
The effect of thallium acetate administration on monoaminergic pathways was studied in male Wistar rats using 30 mg/kg and 50 mg/kg acute IP doses. We found that thallium activated both monoamine oxidase (MAO) activity and serotonin turnover rate in rat brain regions, that may contribute to the neuronal damage mechanism of the agent.Web
ادامه مطلب
The data strongly supported that the thallium(I)‐induced liver toxicity is a result of the disruptive effect of this metal on the mitochondrial respiratory complexes (I, II, and IV), which are the obvious causes of metal‐induced ROS formation and ATP depletion. Thallium(I) is a highly toxic heavy metal; however, up to now, its mechanisms are poorly …Web
ادامه مطلب
Background. Stereotaxic procedures in rats are frequently used in neurological research. The commonly used rat brain stereotaxic atlases areThe Rat Brain in Stereotaxic Coordinates, the second most cited book in science, and Stereotaxic Atlas of Rat Brain (in Chinese) which based on Wistar rats of 290 g and SD rats of 225 g, …Web
ادامه مطلب
Thallium is a heavy metal used in the manufacture of electronic components, optical lenses, semiconductor materials, alloys, gamma radiation detection equipment, imitation jewelry, artist's paints, low temperature thermometers, and green fireworks. [ 1, 2, 3] Trace amounts of thallium are used as a contrast agent in the visualization of cardiac ...Web
ادامه مطلب
Delayed effects of thallium in the rat brain: regional changes in lipid peroxidation and behavioral markers, but moderate alterations in antioxidants, after a single administration. ... Brain regional thallium distribution in rats acutely intoxicated with Tl 2 SO 4. Arch. Toxicol., 63 (1989), pp. 34-37.Web
ادامه مطلب
Thallium(Tl+)toxicityhasbeenrelatedwiththegenerationofreactiveoxygenspecies(ROS)andoxidativestress(OS)inthe …Web
ادامه مطلب
Thallium (Tl) is a toxic heavy metal responsible for noxious effects in living organisms. As a pollutant, Tl can be found in the environment at high concentrations, especially in industrial areas. Systemic toxicity induced by this toxic metal can affect cell metabolism, including redox alterations, mitochondrial dysfunction, and activation of apoptotic signaling …Web
ادامه مطلب